Restaurant Desfina is located at 202 3rd St, Cambridge, MA. This business specializes in Family Style Restaurants and has 5 review(s) with a star rating of 4.0. Restaurant Desfina is open Mon, 11am-4pm; Tue, 11am-4pm; Wed, 11am-4pm; Thu, 11am-4pm; Fri, 11am-4pm; Sat, Closed; Sun, Closed and accepts American Express, Diners Club, Discover, Mastercard and Visa.