Rublos Fresh Mexican Grill is located at 16580 Bernardo Center Dr, San Diego, CA. This location is in the Rancho Bernadino neighborhood. This business specializes in Seafood Restaurants. Rublos Fresh Mexican Grill is open Mon, 10am-9pm; Tue, 10am-9pm; Wed, 10am-9pm; Thu, 10am-9pm; Fri, 10am-9pm; Sat, 10am-9pm; Sun, 10am-9pm and accepts All Major Credit Cards, American Express, Cash, Discover,...