Subway is located at 304 Main St, Buffalo, NY. This location is in the Central Business District neighborhood. This business specializes in Sandwiches. Subway is open Mon, 9am-6pm; Tue, 9am-6pm; Wed, 9am-6pm; Thu, 9am-6pm; Fri, 9am-6pm; Sat, 9am-6pm; Sun, 9am-6pm and accepts American Express, Apple Pay, Cash, Discover, Mastercard and Visa.