Tuscano's Grill is located at 8566 Eager Rd, Saint Louis, MO. This location is in the Brentwood neighborhood. This business specializes in Restaurants. Tuscano's Grill is open Mon - Fri, 10:30am - 7:30pm; Sat, Sun, 11am - 7pm and accepts American Express, Cash, Discover, Mastercard and Visa.