US Post Office is located at 4512 King Kennedy St, Carlisle, SC. This business specializes in Post Offices. US Post Office is open Mon, 8:05am-4:05pm; Tue, 8:05am-4:05pm; Wed, 8:05am-4:05pm; Thu, 8:05am-4:05pm; Fri, 8:05am-4:05pm; Sat, 8am-10:05am; Sun, Closed and accepts American Express, Discover, Mastercard and Visa.