US Post Office is located at 104 4Th St, Clarksville, VA. This business specializes in Post Offices. US Post Office is open Mon, 8:05am-5pm ; Tue, 8:05am-5pm ; Wed, 8:05am-5pm ; Thu, 8:05am-5pm ; Fri, 8:05am-5pm ; Sat, 9am-11am ; Sun, Closed. and accepts American Express, Discover and Visa.