US Post Office is located at 101 Church Ave Sw, Roanoke, VA. This business specializes in Post Offices. US Post Office is open Mon, 8am-5pm; Tue, 8am-5pm; Wed, 8am-5pm; Thu, 8am-5pm; Fri, 8am-5pm; Sat, Closed; Sun, Closed and accepts American Express, Discover, Mastercard and Visa.