US Post Office is located at 420 Main St, Silver Plume, CO. This business specializes in Post Offices. US Post Office is open Mon, 8:05am-1pm; Tue, 8:05am-1pm; Wed, 8:05am-1pm; Thu, 8:05am-1pm; Fri, 8:05am-1pm; Sat, Closed; Sun, Closed and accepts American Express, Discover, Mastercard and Visa.